Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target PJ Jakobsson, S Thorén, R Morgenstern, B Samuelsson Proceedings of the National Academy of Sciences 96 (13), 7220-7225, 1999 | 1295 | 1999 |
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin U Harre, D Georgess, H Bang, A Bozec, R Axmann, E Ossipova, ... The Journal of clinical investigation 122 (5), 1791-1802, 2012 | 872 | 2012 |
Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase CE Trebino, JL Stock, CP Gibbons, BM Naiman, TS Wachtmann, ... Proceedings of the National Academy of Sciences 100 (15), 9044-9049, 2003 | 706 | 2003 |
Membrane prostaglandin E synthase-1: a novel therapeutic target B Samuelsson, R Morgenstern, PJ Jakobsson Pharmacological reviews 59 (3), 207-224, 2007 | 702 | 2007 |
Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis WL Smith, Y Urade, PJ Jakobsson Chemical reviews 111 (10), 5821-5865, 2011 | 579 | 2011 |
Common structural features of MAPEG—a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism PJ Jakobsson, R Morgenstern, J Mancini, A Ford-Hutchinson, B Persson Protein Science 8 (3), 689-692, 1999 | 514 | 1999 |
Pathway across the blood–brain barrier M Ek, D Engblom, S Saha, A Blomqvist, PJ Jakobsson, ... Nature 410 (6827), 430-431, 2001 | 483 | 2001 |
Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides KR Kozak, BC Crews, JD Morrow, LH Wang, YH Ma, R Weinander, ... Journal of Biological Chemistry 277 (47), 44877-44885, 2002 | 436 | 2002 |
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss A Krishnamurthy, V Joshua, AH Hensvold, T Jin, M Sun, N Vivar, ... Annals of the rheumatic diseases 75 (4), 721-729, 2016 | 429 | 2016 |
Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells DO Stichtenoth, S Thorén, H Bian, M Peters-Golden, PJ Jakobsson, ... The Journal of Immunology 167 (1), 469-474, 2001 | 383 | 2001 |
Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis D Engblom, S Saha, L Engström, M Westman, LP Audoly, PJ Jakobsson, ... Nature neuroscience 6 (11), 1137-1138, 2003 | 358 | 2003 |
Autoantibodies to citrullinated proteins may induce joint pain independent of inflammation G Wigerblad, DB Bas, C Fernades-Cerqueira, A Krishnamurthy, ... Annals of the rheumatic diseases 75 (4), 730-738, 2016 | 303 | 2016 |
Coordinate up‐and down‐regulation of glutathione‐dependent prostaglandin E synthase and cyclooxygenase‐2 in A549 cells: inhibition by NS‐398 and leukotriene C4 S Thorén, PJ Jakobsson European journal of biochemistry 267 (21), 6428-6434, 2000 | 296 | 2000 |
Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer K Yoshimatsu, D Golijanin, PB Paty, RA Soslow, PJ Jakobsson, ... Clinical Cancer Research 7 (12), 3971-3976, 2001 | 281 | 2001 |
Identification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5 … PJ Jakobsson, JA Mancini, AW Ford-Hutchinson Journal of Biological Chemistry 271 (36), 22203-22210, 1996 | 275 | 1996 |
Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer K Yoshimatsu, NK Altorki, D Golijanin, F Zhang, PJ Jakobsson, ... Clinical Cancer Research 7 (9), 2669-2674, 2001 | 260 | 2001 |
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells H Zirath, A Frenzel, G Oliynyk, L Segerström, UK Westermark, K Larsson, ... Proceedings of the National Academy of Sciences 110 (25), 10258-10263, 2013 | 248 | 2013 |
Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) a widespread protein superfamily PJ Jakobsson, R Morgenstern, J Mancini, A Ford-Hutchinson, B Persson American journal of respiratory and critical care medicine 161 (supplement_1 …, 2000 | 246 | 2000 |
Multiplex analyses of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis M Brink, M Hansson, L Mathsson, PJ Jakobsson, R Holmdahl, ... Arthritis & Rheumatism 65 (4), 899-910, 2013 | 244 | 2013 |
Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in … AH Hensvold, PKE Magnusson, V Joshua, M Hansson, L Israelsson, ... Annals of the rheumatic diseases 74 (2), 375-380, 2015 | 219 | 2015 |