Christopher J Handley
Christopher J Handley
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Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage
DJ McQUILLAN, CJ Handley, MA Campbell, S Bolis, VE Milway, ...
Biochemical Journal 240 (2), 423-430, 1986
Variants within the COL5A1 gene are associated with Achilles tendinopathy in two populations
AV September, J Cook, CJ Handley, L van der Merwe, MP Schwellnus, ...
British journal of sports medicine 43 (5), 357-365, 2009
The effect of serum on biosynthesis of proteoglycans by bovine articular cartilage in culture
VC Hascall, CJ Handley, DJ McQuillan, GK Hascall, HC Robinson, ...
Archives of Biochemistry and Biophysics 224 (1), 206-223, 1983
Mechanism of catabolism of aggrecan by articular cartilage
MZ Ilic, CJ Handley, HC Robinson, MT Mok
Archives of biochemistry and biophysics 294 (1), 115-122, 1992
In vitro response of chondrocytes to mechanical loading. The effect of short term mechanical tension
MT De Witt, CJ Handley, BW Oakes, DA Lowther
Connective tissue research 12 (2), 97-109, 1984
Changes in the composition of the extracellular matrix in patellar tendinopathy
S Tom, J Parkinson, MZ Ilic, J Cook, JA Feller, CJ Handley
Matrix Biology 28 (4), 230-236, 2009
The synthesis of elastin, collagen, and glycosaminoglycans by high density primary cultures of neonatal rat aortic smooth muscle. An ultrastructural and biochemical study.
BW Oakes, AC Batty, CJ Handley, LB Sandberg
European journal of cell biology 27 (1), 34-46, 1982
Expression and activity of ADAMTS‐5 in synovium
MN Vankemmelbeke, I Holen, AG Wilson, MZ Ilic, CJ Handley, GS Kelner, ...
European Journal of Biochemistry 268 (5), 1259-1268, 2001
Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin b and an inhibitor of matrix metalloproteinases. evidence for two converging pathways of …
DJ Buttle, CJ Handley, MZ Ilic, J Saklatvala, M Murata, AJ Barrett
Arthritis & Rheumatism 36 (12), 1709-1717, 1993
Selective inhibition of ADAMTS‐1,‐4 and‐5 by catechin gallate esters
MN Vankemmelbeke, GC Jones, C Fowles, MZ Ilic, CJ Handley, AJ Day, ...
European journal of biochemistry 270 (11), 2394-2403, 2003
Inhibition of proteoglycan biosynthesis by hyaluronic acid in chondrocytes in cell culture
CJ Handley, DA Lowther
Biochimica et Biophysica Acta (BBA)-General Subjects 444 (1), 69-74, 1976
Components of the transforming growth factor-β family and the pathogenesis of human Achilles tendon pathology—a genetic association study
M Posthumus, M Collins, J Cook, CJ Handley, WJ Ribbans, RKW Smith, ...
Rheumatology 49 (11), 2090-2097, 2010
Characterisation of proteoglycans and their catabolic products in tendon and explant cultures of tendon
T Samiric, MZ Ilic, CJ Handley
Matrix biology 23 (2), 127-140, 2004
Turnover of proteoglycans in cultures of bovine articular cartilage
MA Campbell, CJ Handley, VC Hascall, RA Campbell, DA Lowther
Archives of biochemistry and biophysics 234 (1), 275-289, 1984
Oxygen free-radicals mediate an inhibition of proteoglycan synthesis in cultured articular cartilage.
EJ Bates, DA Lowther, CJ Handley
Annals of the rheumatic diseases 43 (3), 462-469, 1984
The apoptosis pathway and the genetic predisposition to Achilles tendinopathy
EM Nell, L van der Merwe, J Cook, CJ Handley, M Collins, AV September
Journal of Orthopaedic Research 30 (11), 1719-1724, 2012
Change in proteoglycan metabolism is a characteristic of human patellar tendinopathy
J Parkinson, T Samiric, MZ Ilic, J Cook, JA Feller, CJ Handley
Arthritis & Rheumatism 62 (10), 3028-3035, 2010
Involvement of proteoglycans in tendinopathy
J Parkinson, T Samiric, MZ Ilic, J Cook, CJ Handley
The Journal of Musculoskeletal and Neuronal Interactions 11 (2), 86-93, 2011
The oxidant hypochlorite (OCl−), a product of the myeloperoxidase system, degrades articular cartilage proteoglycan aggregate
M Katrantzis, MS Baker, CJ Handley, DA Lowther
Free Radical Biology and Medicine 10 (2), 101-109, 1991
Effects of free and bound insulin‐like growth factors on proteoglycan metabolism in articular cartilage explants
GH Tesch, CJ Handley, HJ Cornell, AC Herington
Journal of orthopaedic research 10 (1), 14-22, 1992
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