Systematic discovery of Rab GTPases with synaptic functions in Drosophila CC Chan, S Scoggin, D Wang, S Cherry, T Dembo, B Greenberg, EJ Jin, ... Current Biology 21 (20), 1704-1715, 2011 | 139 | 2011 |
Charcot-Marie-Tooth 2B mutations in rab7 cause dosage-dependent neurodegeneration due to partial loss of function S Cherry, EJ Jin, MN Özel, Z Lu, E Agi, D Wang, WH Jung, D Epstein, ... Elife 2, e01064, 2013 | 90 | 2013 |
A recurrent WARS mutation is a novel cause of autosomal dominant distal hereditary motor neuropathy PC Tsai, BW Soong, I Mademan, YH Huang, CR Liu, CT Hsiao, HT Wu, ... Brain 140 (5), 1252-1266, 2017 | 89 | 2017 |
Membrane trafficking in neuronal maintenance and degeneration D Wang, CC Chan, S Cherry, PR Hiesinger Cellular and molecular life sciences 70, 2919-2934, 2013 | 79 | 2013 |
Mutations in the Human naked cuticle Homolog NKD1 Found in Colorectal Cancer Alter Wnt/Dvl/β-Catenin Signaling J Guo, T Cagatay, G Zhou, CC Chan, S Blythe, K Suyama, L Zheng, K Pan, ... PloS one 4 (11), e7982, 2009 | 59 | 2009 |
Atg9 antagonizes TOR signaling to regulate intestinal cell growth and epithelial homeostasis in Drosophila JK Wen, YT Wang, CC Chan, CW Hsieh, HM Liao, CC Hung, GC Chen Elife 6, e29338, 2017 | 50 | 2017 |
Strategies for gene disruption in Drosophila SC Lin, YY Chang, CC Chan Cell & bioscience 4, 1-9, 2014 | 46 | 2014 |
Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy CH Lin, PI Tsai, HY Lin, N Hattori, M Funayama, B Jeon, K Sato, K Abe, ... Brain 143 (11), 3352-3373, 2020 | 45 | 2020 |
Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length SY Chung, MS Vining, PL Bradley, CC Chan, KA Wharton Jr, DJ Andrew PLoS genetics 5 (11), e1000746, 2009 | 44 | 2009 |
Lipophagy prevents activity‐dependent neurodegeneration due to dihydroceramide accumulation in vivo WH Jung, CC Liu, YL Yu, YC Chang, WY Lien, HC Chao, SY Huang, ... EMBO reports 18 (7), 1150-1165, 2017 | 35 | 2017 |
Possible mechanism (s) of arachidonic acid–induced intracellular acidosis in rat cardiac myocytes ML Wu, CC Chan, MJ Su Circulation Research 86 (3), e55-e62, 2000 | 33 | 2000 |
Mitochondrial function and Parkinson’s disease: from the perspective of the electron transport chain JL Li, TY Lin, PL Chen, TN Guo, SY Huang, CH Chen, CH Lin, CC Chan Frontiers in molecular neuroscience 14, 797833, 2021 | 32 | 2021 |
An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle S Waldrop, CC Chan, T Cagatay, S Zhang, R Rousset, J Mack, W Zeng, ... Genetics 174 (1), 331-348, 2006 | 30 | 2006 |
Similarities of Drosophila rab GTPases Based on Expression Profiling: Completion and Analysis of the rab-Gal4 Kit EJ Jin, CC Chan, E Agi, S Cherry, E Hanacik, M Buszczak, PR Hiesinger PLoS One 7 (7), e40912, 2012 | 27 | 2012 |
Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies FE Kohrs, IM Daumann, B Pavlovic, EJ Jin, FR Kiral, SC Lin, F Port, ... Elife 10, e59594, 2021 | 24 | 2021 |
Drosophila Naked cuticle (Nkd) engages the nuclear import adaptor Importin-α3 to antagonize Wnt/β-catenin signaling CC Chan, S Zhang, R Rousset, KA Wharton Jr Developmental biology 318 (1), 17-28, 2008 | 24 | 2008 |
Differential protective effects of connective tissue growth factor against Aβ neurotoxicity on neurons and glia CN Yang, MF Wu, CC Liu, WH Jung, YC Chang, WP Lee, YJ Shiao, ... Human molecular genetics 26 (20), 3909-3921, 2017 | 23 | 2017 |
Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling KY Lin, WD Wang, CH Lin, E Rastegari, YH Su, YT Chang, YF Liao, ... Nature communications 11 (1), 3147, 2020 | 21 | 2020 |
UQCRC1 Engages Cytochrome C for Neuronal Apoptotic Cell Death YC Hung, KL Huang, PL Chen, HY Lin, HA Lu, WC Lo, TT Lee, TY Lin, ... Cell Reports 36 (12), 109729, 2021 | 19 | 2021 |
Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress FY Tzou, TY Su, WS Lin, HC Kuo, YL Yu, YH Yeh, CC Liu, CH Kuo, ... Cell reports 35 (2), 2021 | 16 | 2021 |