| Protein expression from exogenous mRNA: uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway C Lorenz, M Fotin-Mleczek, G Roth, C Becker, TC Dam, WPR Verdurmen, ... RNA biology 8 (4), 627-636, 2011 | 200 | 2011 |
| Cellular integration of an enzyme-loaded polymersome nanoreactor SFM Van Dongen, WPR Verdurmen, R Peters, RJM Nolte, R Brock, ... Angew. Chem., Int. Ed 49 (40), 7213-7216, 2010 | 163 | 2010 |
| Molecular parameters of siRNA–cell penetrating peptide nanocomplexes for efficient cellular delivery AH van Asbeck, A Beyerle, H McNeill, PHM Bovee-Geurts, S Lindberg, ... ACS nano 7 (5), 3797-3807, 2013 | 162 | 2013 |
| Preferential uptake of L-versus D-amino acid cell-penetrating peptides in a cell type-dependent manner WPR Verdurmen, PH Bovee-Geurts, P Wadhwani, AS Ulrich, M Hällbrink, ... Chemistry & biology 18 (8), 1000-1010, 2011 | 155 | 2011 |
| A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency F Duchardt, IR Ruttekolk, WPR Verdurmen, H Lortat-Jacob, J Bürck, ... Journal of Biological Chemistry 284 (52), 36099-36108, 2009 | 147 | 2009 |
| Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase: implications for uptake WPR Verdurmen, M Thanos, IR Ruttekolk, E Gulbins, R Brock Journal of Controlled Release 147 (2), 171-179, 2010 | 123 | 2010 |
| Biological responses towards cationic peptides and drug carriers WPR Verdurmen, R Brock Trends in pharmacological sciences 32 (2), 116-124, 2011 | 104 | 2011 |
| A quantitative comparison of cytosolic delivery via different protein uptake systems WPR Verdurmen, M Mazlami, A Plückthun Scientific reports 7 (1), 13194, 2017 | 96 | 2017 |
| Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure S Dinkla, K Wessels, WPR Verdurmen, C Tomelleri, JCA Cluitmans, ... Cell death & disease 3 (10), e410-e410, 2012 | 87 | 2012 |
| Efficient cell-specific uptake of binding proteins into the cytoplasm through engineered modular transport systems WPR Verdurmen, M Luginbühl, A Honegger, A Plückthun Journal of controlled release 200, 13-22, 2015 | 81 | 2015 |
| The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides R Wallbrecher, WPR Verdurmen, S Schmidt, PH Bovee-Geurts, ... Cellular and molecular life sciences 71, 2717-2729, 2014 | 67 | 2014 |
| Mimicking Tumors: Toward More Predictive In Vitro Models for Peptide- and Protein-Conjugated Drugs D van den Brand, LF Massuger, R Brock, WPR Verdurmen Bioconjugate chemistry 28 (3), 846-856, 2017 | 55 | 2017 |
| Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state S Fanghänel, P Wadhwani, E Strandberg, WPR Verdurmen, J Bürck, ... PLoS One 9 (6), e99653, 2014 | 55 | 2014 |
| Cell surface clustering of heparan sulfate proteoglycans by amphipathic cell-penetrating peptides does not contribute to uptake WPR Verdurmen, R Wallbrecher, S Schmidt, J Eilander, P Bovee-Geurts, ... Journal of controlled release 170 (1), 83-91, 2013 | 49 | 2013 |
| Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS–p110 crosstalk R Tamaskovic, M Schwill, G Nagy-Davidescu, C Jost, DC Schaefer, ... Nature Communications 7 (1), 11672, 2016 | 46 | 2016 |
| Detecting cytosolic peptide delivery with the GFP complementation assay in the low micromolar range S Schmidt, MJW Adjobo‐Hermans, R Wallbrecher, WPR Verdurmen, ... Angewandte Chemie International Edition 54 (50), 15105-15108, 2015 | 41 | 2015 |
| Exploration of the design principles of a cell-penetrating bicylic peptide scaffold R Wallbrecher, L Depré, WPR Verdurmen, PH Bovée-Geurts, ... Bioconjugate chemistry 25 (5), 955-964, 2014 | 41 | 2014 |
| Metabolic switching of tumor cells under hypoxic conditions in a tumor-on-a-chip model V Palacio-Castañeda, L Kooijman, B Venzac, WPR Verdurmen, S Le Gac Micromachines 11 (4), 382, 2020 | 37 | 2020 |
| Multivalent presentation of the cell-penetrating peptide nona-arginine on a linear scaffold strongly increases its membrane-perturbing capacity A Chakrabarti, JJ Witsenburg, MD Sinzinger, M Richter, R Wallbrecher, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (12), 3097-3106, 2014 | 30 | 2014 |
| The intracellular pharmacokinetics of terminally capped peptides IR Ruttekolk, JJ Witsenburg, H Glauner, PHM Bovee-Geurts, ES Ferro, ... Molecular pharmaceutics 9 (5), 1077-1086, 2012 | 29 | 2012 |
