| Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice CJ Wruck, A Fragoulis, A Gurzynski, LO Brandenburg, YW Kan, K Chan, ... Annals of the rheumatic diseases 70 (5), 844-850, 2011 | 306 | 2011 |
| Nrf2 in health and disease: current and future clinical implications O Al-Sawaf, T Clarner, A Fragoulis, YW Kan, T Pufe, K Streetz, CJ Wruck Clinical science 129 (12), 989-999, 2015 | 130 | 2015 |
| Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia N Kweider, A Fragoulis, C Rosen, U Pecks, W Rath, T Pufe, CJ Wruck Journal of Biological Chemistry 286 (50), 42863-42872, 2011 | 117 | 2011 |
| Widespread post-transcriptional attenuation of genomic copy-number variation in cancer E Gonçalves, A Fragoulis, L Garcia-Alonso, T Cramer, J Saez-Rodriguez, ... Cell systems 5 (4), 386-398. e4, 2017 | 105 | 2017 |
| Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model T Draheim, A Liessem, M Scheld, F Wilms, M Weißflog, B Denecke, ... Glia 64 (12), 2219-2230, 2016 | 92 | 2016 |
| The cancer stem cell subtype determines immune infiltration of glioblastoma CP Beier, P Kumar, K Meyer, P Leukel, V Bruttel, I Aschenbrenner, ... Stem cells and development 21 (15), 2753-2761, 2012 | 91 | 2012 |
| Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease A Fragoulis, S Siegl, M Fendt, S Jansen, U Soppa, LO Brandenburg, ... Redox biology 12, 843-853, 2017 | 76 | 2017 |
| Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats J Dang, LO Brandenburg, C Rosen, A Fragoulis, M Kipp, T Pufe, C Beyer, ... Journal of Molecular Neuroscience 46, 578-584, 2012 | 67 | 2012 |
| Nrf2 augments skeletal muscle regeneration after ischaemia–reperfusion injury O Al‐Sawaf, A Fragoulis, C Rosen, N Keimes, EA Liehn, F Hölzle, ... The Journal of pathology 234 (4), 538-547, 2014 | 66 | 2014 |
| Enoxaparin prevents steroid-related avascular necrosis of the femoral head R Beckmann, H Shaheen, N Kweider, A Ghassemi, A Fragoulis, ... The Scientific World Journal 2014, 2014 | 60 | 2014 |
| Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes A Fragoulis, J Laufs, S Müller, U Soppa, S Siegl, LK Reiss, ... Arthritis research & therapy 14, 1-10, 2012 | 59 | 2012 |
| Role of Nrf2 in fracture healing: clinical aspects of oxidative stress Y Kubo, CJ Wruck, A Fragoulis, W Drescher, HC Pape, P Lichte, H Fischer, ... Calcified tissue international 105 (4), 341-352, 2019 | 57 | 2019 |
| Mechanical forces induce changes in VEGF and VEGFR-1/sFlt-1 expression in human chondrocytes R Beckmann, A Houben, M Tohidnezhad, N Kweider, A Fragoulis, ... International journal of molecular sciences 15 (9), 15456-15474, 2014 | 55 | 2014 |
| Nrf2 is a central regulator of metabolic reprogramming of myeloid-derived suppressor cells in steady state and sepsis K Ohl, A Fragoulis, P Klemm, J Baumeister, W Klock, E Verjans, S Böll, ... Frontiers in immunology 9, 1552, 2018 | 50 | 2018 |
| Hepatocyte-specific Keap1 deletion reduces liver steatosis but not inflammation during non-alcoholic steatohepatitis development P Ramadori, H Drescher, S Erschfeld, F Schumacher, C Berger, ... Free Radical Biology and Medicine 91, 114-126, 2016 | 49 | 2016 |
| Nrf2 deficiency increases oligodendrocyte loss, demyelination, neuroinflammation and axonal damage in an MS animal model A Nellessen, S Nyamoya, A Zendedel, A Slowik, C Wruck, C Beyer, ... Metabolic Brain Disease 35, 353-362, 2020 | 42 | 2020 |
| Platelet-released growth factors modulate the secretion of cytokines in synoviocytes under inflammatory joint disease M Tohidnezhad, A Bayer, B Rasuo, JVP Hock, N Kweider, A Fragoulis, ... Mediators of inflammation 2017, 2017 | 39 | 2017 |
| Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis N Rohwer, S Jumpertz, M Erdem, A Egners, KT Warzecha, A Fragoulis, ... Oncogene 38 (28), 5670-5685, 2019 | 34 | 2019 |
| Macrophages protect against loss of adipose tissue during cancer cachexia M Erdem, D Möckel, S Jumpertz, C John, A Fragoulis, I Rudolph, ... Journal of cachexia, sarcopenia and muscle 10 (5), 1128-1142, 2019 | 33 | 2019 |
| Nrf2 protects against TWEAK-mediated skeletal muscle wasting O Al-Sawaf, A Fragoulis, C Rosen, YW Kan, TT Sönmez, T Pufe, CJ Wruck Scientific reports 4 (1), 3625, 2014 | 24 | 2014 |
Christoph Jan WruckDozent Anatomie RWTH AachenVerified email at ukaachen.de
