Tyler J. Gorrie-Stone
Tyler J. Gorrie-Stone
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Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array
G Mansell, TJ Gorrie-Stone, Y Bao, M Kumari, LS Schalkwyk, J Mill, ...
BMC genomics 20 (1), 1-15, 2019
Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits
E Hannon, TJ Gorrie-Stone, MC Smart, J Burrage, A Hughes, Y Bao, ...
The American Journal of Human Genetics 103 (5), 654-665, 2018
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
Nature genetics 53 (9), 1311-1321, 2021
Socioeconomic position and DNA methylation age acceleration across the life course
A Hughes, M Smart, T Gorrie-Stone, E Hannon, J Mill, Y Bao, J Burrage, ...
American journal of epidemiology 187 (11), 2346-2354, 2018
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE DÝaz, ID Young, ...
Science advances 7 (16), eabf8711, 2021
Systematic underestimation of the epigenetic clock and age acceleration in older subjects
LY El Khoury, T Gorrie-Stone, M Smart, A Hughes, Y Bao, A Andrayas, ...
Genome biology 20 (1), 1-10, 2019
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase
JA Newman, A Douangamath, S Yadzani, Y Yosaatmadja, A Aimon, ...
Nature communications 12 (1), 1-11, 2021
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell stem cell 29 (2), 217-231. e8, 2022
Bigmelon: tools for analysing large DNA methylation datasets
TJ Gorrie-Stone, MC Smart, A Saffari, K Malki, E Hannon, J Burrage, J Mill, ...
Bioinformatics 35 (6), 981-986, 2019
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machineá…
H Achdout, A Aimon, E Bar-David, H Barr, A Ben-Shmuel, J Bennett, ...
BioRxiv, 2020
Achieving efficient fragment screening at XChem facility at diamond light source
A Douangamath, A Powell, D Fearon, PM Collins, R Talon, T Krojer, ...
JoVE (Journal of Visualized Experiments), e62414, 2021
DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy
Y Wang, E Hannon, OA Grant, TJ Gorrie-Stone, M Kumari, J Mill, X Zhai, ...
BMC genomics 22 (1), 1-11, 2021
Tyrosine intake and cardiovascular responses in a motivated performance situation.
A Hase, T Gorrie-Stone, P Freeman
Sport, Exercise, and Performance Psychology 8 (1), 80, 2019
Open science discovery of oral non-covalent SARS-CoV-2 main protease inhibitor therapeutics
H Achdout, A Aimon, E Bar-David, H Barr, A Ben-Shmuel, J Bennett, ...
The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations
F ┼senius, TJ Gorrie-Stone, A Brew, Y Panchbhaya, E Williamson, ...
PLoS genetics 16 (10), e1009035, 2020
Properties of the epigenetic clock and age acceleration
L El Khoury, T Gorrie-Stone, M Smart, A Hughes, Y Bao, A Andrayas, ...
bioRxiv, 363143, 2018
DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effects
F ┼senius, TJ Gorrie-Stone, A Brew, Y Panchbaya, E Williamson, ...
BioRxiv, 2020
DNA Methylation: Methods and Analyses
TJ Gorrie-Stone
University of Essex, 2019
InterpolatedXY: a two-step strategy to normalize DNA methylation microarray data avoiding sex bias
Y Wang, TJ Gorrie-Stone, OA Grant, AD Andrayas, X Zhai, ...
Bioinformatics 38 (16), 3950-3957, 2022
Uncertainty quantification of reference based cellular deconvolution algorithms
G Shireby, A MacCalman, EL Dempster, J Burrage, T Gorrie-Stone, ...
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