Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array G Mansell, TJ Gorrie-Stone, Y Bao, M Kumari, LS Schalkwyk, J Mill, ... BMC genomics 20 (1), 1-15, 2019 | 138 | 2019 |
Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits E Hannon, TJ Gorrie-Stone, MC Smart, J Burrage, A Hughes, Y Bao, ... The American Journal of Human Genetics 103 (5), 654-665, 2018 | 98 | 2018 |
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ... Nature genetics 53 (9), 1311-1321, 2021 | 81 | 2021 |
Socioeconomic position and DNA methylation age acceleration across the life course A Hughes, M Smart, T Gorrie-Stone, E Hannon, J Mill, Y Bao, J Burrage, ... American journal of epidemiology 187 (11), 2346-2354, 2018 | 55 | 2018 |
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 54 | 2021 |
Systematic underestimation of the epigenetic clock and age acceleration in older subjects LY El Khoury, T Gorrie-Stone, M Smart, A Hughes, Y Bao, A Andrayas, ... Genome biology 20 (1), 1-10, 2019 | 52 | 2019 |
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase JA Newman, A Douangamath, S Yadzani, Y Yosaatmadja, A Aimon, ... Nature communications 12 (1), 1-11, 2021 | 49 | 2021 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 33 | 2022 |
Bigmelon: tools for analysing large DNA methylation datasets TJ Gorrie-Stone, MC Smart, A Saffari, K Malki, E Hannon, J Burrage, J Mill, ... Bioinformatics 35 (6), 981-986, 2019 | 33 | 2019 |
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine … H Achdout, A Aimon, E Bar-David, H Barr, A Ben-Shmuel, J Bennett, ... BioRxiv, 2020 | 31 | 2020 |
Achieving efficient fragment screening at XChem facility at diamond light source A Douangamath, A Powell, D Fearon, PM Collins, R Talon, T Krojer, ... JoVE (Journal of Visualized Experiments), e62414, 2021 | 8 | 2021 |
DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy Y Wang, E Hannon, OA Grant, TJ Gorrie-Stone, M Kumari, J Mill, X Zhai, ... BMC genomics 22 (1), 1-11, 2021 | 6 | 2021 |
Tyrosine intake and cardiovascular responses in a motivated performance situation. A Hase, T Gorrie-Stone, P Freeman Sport, Exercise, and Performance Psychology 8 (1), 80, 2019 | 6 | 2019 |
Open science discovery of oral non-covalent SARS-CoV-2 main protease inhibitor therapeutics H Achdout, A Aimon, E Bar-David, H Barr, A Ben-Shmuel, J Bennett, ... | 5 | 2020 |
The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations F Åsenius, TJ Gorrie-Stone, A Brew, Y Panchbhaya, E Williamson, ... PLoS genetics 16 (10), e1009035, 2020 | 5 | 2020 |
Properties of the epigenetic clock and age acceleration L El Khoury, T Gorrie-Stone, M Smart, A Hughes, Y Bao, A Andrayas, ... bioRxiv, 363143, 2018 | 5 | 2018 |
DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effects F Åsenius, TJ Gorrie-Stone, A Brew, Y Panchbaya, E Williamson, ... BioRxiv, 2020 | 2 | 2020 |
DNA Methylation: Methods and Analyses TJ Gorrie-Stone University of Essex, 2019 | 2 | 2019 |
InterpolatedXY: a two-step strategy to normalize DNA methylation microarray data avoiding sex bias Y Wang, TJ Gorrie-Stone, OA Grant, AD Andrayas, X Zhai, ... Bioinformatics 38 (16), 3950-3957, 2022 | 1 | 2022 |
Uncertainty quantification of reference based cellular deconvolution algorithms G Shireby, A MacCalman, EL Dempster, J Burrage, T Gorrie-Stone, ... | | 2022 |