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Yang Xiang
Yang Xiang
PMI, Manager and team leader of computational biology and modeling
Verified email at pmi.com
Title
Cited by
Cited by
Year
Generalized simulated annealing for global optimization: the GenSA package.
Y Xiang, S Gubian, B Suomela, J Hoeng
R J. 5 (1), 13, 2013
4022013
Generalized simulated annealing algorithm and its application to the Thomson model
Y Xiang, DY Sun, W Fan, XG Gong
Physics Letters A 233 (3), 216-220, 1997
2591997
Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers
C Mathis, C Poussin, D Weisensee, S Gebel, A Hengstermann, A Sewer, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 304 (7 …, 2013
1602013
Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge
AL Tarca, M Lauria, M Unger, E Bilal, S Boue, K Kumar Dey, J Hoeng, ...
Bioinformatics 29 (22), 2892-2899, 2013
1312013
Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by …
B Phillips, B Titz, U Kogel, D Sharma, P Leroy, Y Xiang, G Vuillaume, ...
Food and chemical toxicology 109, 315-332, 2017
1282017
Efficiency of generalized simulated annealing
Y Xiang, XG Gong
Physical Review E 62 (3), 4473, 2000
1262000
Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models
F Martin, A Sewer, M Talikka, Y Xiang, J Hoeng, MC Peitsch
BMC bioinformatics 15, 1-24, 2014
1122014
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with …
ET Wong, U Kogel, E Veljkovic, F Martin, Y Xiang, S Boue, G Vuillaume, ...
Regulatory Toxicology and Pharmacology 81, S59-S81, 2016
922016
A framework for in vitro systems toxicology assessment of e-liquids
AR Iskandar, I Gonzalez-Suarez, S Majeed, D Marescotti, A Sewer, ...
Toxicology Mechanisms and Methods 26 (6), 392-416, 2016
912016
Generalized Simulated Annealing Studies on Structures and Properties of Nin (n = 255) Clusters
Y Xiang, DY Sun, XG Gong
The Journal of Physical Chemistry A 104 (12), 2746-2751, 2000
832000
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared …
U Kogel, WK Schlage, F Martin, Y Xiang, S Ansari, P Leroy, ...
Food and chemical toxicology 68, 204-217, 2014
812014
Case study: the role of mechanistic network models in systems toxicology
J Hoeng, M Talikka, F Martin, A Sewer, X Yang, A Iskandar, WK Schlage, ...
Drug Discovery Today 19 (2), 183-192, 2014
782014
3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product
AR Iskandar, C Mathis, F Martin, P Leroy, A Sewer, S Majeed, D Kuehn, ...
ALTEX-Alternatives to animal experimentation 34 (1), 23-48, 2017
682017
A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human …
AR Iskandar, C Mathis, WK Schlage, S Frentzel, P Leroy, Y Xiang, ...
Toxicology in vitro 39, 29-51, 2017
632017
Impact assessment of cigarette smoke exposure on organotypic bronchial epithelial tissue cultures: a comparison of mono-culture and coculture model containing fibroblasts
AR Iskandar, Y Xiang, S Frentzel, M Talikka, P Leroy, D Kuehn, E Guedj, ...
Toxicological Sciences 147 (1), 207-221, 2015
612015
In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue …
WK Schlage, AR Iskandar, R Kostadinova, Y Xiang, A Sewer, S Majeed, ...
Toxicology mechanisms and methods 24 (7), 470-487, 2014
602014
Evaluation of the Tobacco Heating System 2.2 (THS2. 2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2. 2 aerosol causes reduced …
A Sewer, U Kogel, M Talikka, ET Wong, F Martin, Y Xiang, E Guedj, ...
Regulatory toxicology and pharmacology 81, S82-S92, 2016
512016
Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells
U Kogel, IG Suarez, Y Xiang, E Dossin, PA Guy, C Mathis, D Marescotti, ...
Toxicology in Vitro 29 (8), 2102-2115, 2015
432015
The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure
M Talikka, R Kostadinova, Y Xiang, C Mathis, A Sewer, S Majeed, ...
International Journal of Toxicology 33 (6), 506-517, 2014
422014
A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke
J Szostak, ET Wong, B Titz, T Lee, SK Wong, T Low, KM Lee, J Zhang, ...
American Journal of Physiology-Heart and Circulatory Physiology 318 (3 …, 2020
402020
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