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John Takyi-Williams
John Takyi-Williams
Pharmacokinetics and Mass Spectrometry Core, University of Michigan
Verified email at e.ntu.edu.sg
Title
Cited by
Cited by
Year
Ambient ionization MS for bioanalysis: recent developments and challenges
J Takyi-Williams, CF Liu, K Tang
Bioanalysis 7 (15), 1901-1923, 2015
342015
Genetic incorporation of 1, 2-aminothiol functionality for site-specific protein modification via thiazolidine formation
X Bi, KK Pasunooti, AH Tareq, J Takyi-Williams, CF Liu
Organic & biomolecular chemistry 14 (23), 5282-5285, 2016
242016
Application of paper spray–MS in PK studies using sunitinib and benzethonium as model compounds
J Takyi-Williams, X Dong, H Gong, Y Wang, W Jian, CF Liu, K Tang
Bioanalysis 7 (4), 413-423, 2015
242015
Discovery of ARD-2051 as a potent and orally efficacious proteolysis targeting chimera (PROTAC) degrader of androgen receptor for the treatment of advanced prostate cancer
X Han, L Zhao, W Xiang, B Miao, C Qin, M Wang, T Xu, D McEachern, ...
Journal of Medicinal Chemistry 66 (13), 8822-8843, 2023
142023
Development and validation of a LC-HRMS method for the quantification of cannabinoids and their metabolites in human plasma
MK Mohamed, J Takyi-Williams, B Baudot, A Grobler
European Journal of Pharmaceutical Sciences 159, 105705, 2021
132021
Assessment of paper tip angular position, carryover, matrix effects and dried blood spot storage effect on paper spray mass spectrometry
J Takyi-Williams, W Jian, Y Wang, K Tang, H Gong, CF Liu
Analytical methods 12 (6), 747-757, 2020
62020
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR+ Human Prostate Cancer
W Xiang, L Zhao, X Han, T Xu, S Kregel, M Wang, B Miao, C Qin, M Wang, ...
Journal of Medicinal Chemistry 66 (18), 13280-13303, 2023
52023
Volumetric absorptive microsampling to enhance the therapeutic drug monitoring of tacrolimus and mycophenolic acid: a systematic review and critical assessment
AD Leino, J Takyi-Williams, MP Pai
Therapeutic Drug Monitoring 45 (4), 463-478, 2023
42023
Design and synthesis of orally active quinolyl pyrazinamides as Sigma 2 receptor ligands for the treatment of pancreatic cancer
J Roy, A Kyani, M Hanafi, Y Xu, J Takyi-Williams, D Sun, EEA Osman, ...
Journal of Medicinal Chemistry 66 (3), 1990-2019, 2023
42023
Application of a new volumetric microsampling device for quantitative bioanalysis of immunosuppression
AD Leino, J Takyi-Williams, B Wen, D Sun, MP Pai
Bioanalysis 14 (17), 1141-1152, 2022
42022
Household representative sample strategy for COVID-19 large-scale population screening
J Takyi-Williams
Medical Hypotheses 144, 110200, 2020
32020
Discovery of CBPD-268 as an exceptionally potent and orally efficacious CBP/p300 PROTAC degrader capable of achieving tumor regression
Z Chen, M Wang, D Wu, L Bai, T Xu, H Metwally, Y Wang, D McEachern, ...
Journal of Medicinal Chemistry 67 (7), 5275-5304, 2024
12024
Insights into Peptidoglycan-Targeting Radiotracers for Imaging Bacterial Infections: Updates, Challenges, and Future Perspectives
PC Koatale, MM Welling, H Ndlovu, M Kgatle, S Mdanda, A Mdlophane, ...
ACS Infectious Diseases, 2024
12024
Development and validation of an LC-MS/MS method for the quantification of goserelin in a Pheroid® formulation, in simulated intestinal fluid
J Takyi-Williams, L Erasmus, R Hayeshi, A Grobler
Journal of Pharmaceutical and Biomedical Analysis 180, 113044, 2020
12020
Discovery of CBPD-409 and CBPD-268 as highly potent and orally efficacious CBP/p300 PROTAC degraders for the treatment of castration-resistant prostate cancer
Z Chen, M Wang, D Wu, L Zhao, T Xu, H Metwally, Y Wang, D McEachern, ...
Cancer Research 84 (6_Supplement), 4504-4504, 2024
2024
Bioanalysis of six antibiotics from volumetric microsamples: a new tool for precision dosing in critically ill children
J Takyi-Williams, AD Leino, R Li, KJ Downes, AF Zuppa, A Bwint, B Wen, ...
Bioanalysis 16 (1), 19-31, 2024
2024
Novel Myc-dependent compound DL78 selectively induces mitotic catastrophe and cell death in high grade serous ovarian cancer
J Teitel, M Cusato, M Farah, A Gandhi, P Lee, A White, J Takyi-Williams, ...
Cancer Research 83 (7_Supplement), 1570-1570, 2023
2023
Analytical Methods
J Takyi-Williams, CF Liu
2020
Development of an LC-MS/MS method for the quantification of goserelin from Pheroid® formulation
J Takyi-Williams, L Erasmus, R Hayeshi, A Grobler, M Magwaza
Elsevier, 2019
2019
Safety pharmacology of herbal medicines in South Africa
A Okem, J Takyi-Williams, R Van Wyk, A Grobler
Elsevier, 2019
2019
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