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Karl-Heinz Storbeck
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11-Oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome
MW O’Reilly, P Kempegowda, C Jenkinson, AE Taylor, JL Quanson, ...
The Journal of Clinical Endocrinology & Metabolism 102 (3), 840-848, 2017
1702017
11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: a putative role in castration resistant prostate cancer?
KH Storbeck, LM Bloem, D Africander, L Schloms, P Swart, AC Swart
Molecular and cellular endocrinology 377 (1-2), 135-146, 2013
1432013
Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review
L Schiffer, L Barnard, ES Baranowski, LC Gilligan, AE Taylor, W Arlt, ...
The Journal of steroid biochemistry and molecular biology 194, 105439, 2019
1222019
Intracrine androgen biosynthesis, metabolism and action revisited
L Schiffer, W Arlt, KH Storbeck
Molecular and cellular endocrinology 465, 4-26, 2018
1142018
A new dawn for androgens: novel lessons from 11-oxygenated C19 steroids
E Pretorius, W Arlt, KH Storbeck
Molecular and cellular endocrinology 441, 76-85, 2017
1042017
The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: quantification of steroid intermediates and end products in H295R cells
L Schloms, KH Storbeck, P Swart, WCA Gelderblom, AC Swart
The Journal of steroid biochemistry and molecular biology 128 (3-5), 128-138, 2012
1002012
11-Ketotestosterone and 11-ketodihydrotestosterone in castration resistant prostate cancer: potent androgens which can no longer be ignored
E Pretorius, DJ Africander, M Vlok, MS Perkins, J Quanson, KH Storbeck
PloS one 11 (7), e0159867, 2016
982016
11β-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione
AC Swart, L Schloms, KH Storbeck, LM Bloem, T du Toit, JL Quanson, ...
The Journal of steroid biochemistry and molecular biology 138, 132-142, 2013
782013
High-throughput analysis of 19 endogenous androgenic steroids by ultra-performance convergence chromatography tandem mass spectrometry
JL Quanson, MA Stander, E Pretorius, C Jenkinson, AE Taylor, ...
Journal of Chromatography B 1031, 131-138, 2016
682016
11β-Hydroxyandrostenedione: downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways
AC Swart, KH Storbeck
Molecular and cellular endocrinology 408, 114-123, 2015
622015
11β-hydroxyandrostenedione returns to the steroid arena: biosynthesis, metabolism and function
LM Bloem, KH Storbeck, L Schloms, AC Swart
Molecules 18 (11), 13228-13244, 2013
592013
A comparative study of the androgenic properties of progesterone and the progestins, medroxyprogesterone acetate (MPA) and norethisterone acetate (NET-A)
DJ Africander, KH Storbeck, JP Hapgood
The Journal of steroid biochemistry and molecular biology 143, 404-415, 2014
552014
Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas
LM Bloem, KH Storbeck, P Swart, T du Toit, L Schloms, AC Swart
The Journal of steroid biochemistry and molecular biology 153, 80-92, 2015
512015
A single amino acid residue, Ala 105, confers 16α-hydroxylase activity to human cytochrome P450 17α-hydroxylase/17, 20 lyase
AC Swart, KH Storbeck, P Swart
The Journal of steroid biochemistry and molecular biology 119 (3-5), 112-120, 2010
482010
Modified-release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia
CM Jones, A Mallappa, N Reisch, N Nikolaou, N Krone, BA Hughes, ...
The Journal of Clinical Endocrinology & Metabolism 102 (6), 1797-1806, 2017
462017
Cytochrome b5: novel roles in steroidogenesis
KH Storbeck, AC Swart, P Goosen, P Swart
Molecular and cellular endocrinology 371 (1-2), 87-99, 2013
462013
Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism
KH Storbeck, L Schiffer, ES Baranowski, V Chortis, A Prete, L Barnard, ...
Endocrine reviews 40 (6), 1605-1625, 2019
452019
The development of an ultra performance liquid chromatography-coupled atmospheric pressure chemical ionization mass spectrometry assay for seven adrenal steroids
KH Storbeck, NW Kolar, M Stander, AC Swart, D Prevoo, P Swart
Analytical biochemistry 372 (1), 11-20, 2008
362008
The utility of ultra-high performance supercritical fluid chromatography–tandem mass spectrometry (UHPSFC-MS/MS) for clinically relevant steroid analysis
KH Storbeck, L Gilligan, C Jenkinson, ES Baranowski, JL Quanson, W Arlt, ...
Journal of Chromatography B 1085, 36-41, 2018
352018
11-Oxygenated androgen precursors are the preferred substrates for aldo-keto reductase 1C3 (AKR1C3): implications for castration resistant prostate cancer
M Barnard, JL Quanson, E Mostaghel, E Pretorius, JL Snoep, ...
The Journal of steroid biochemistry and molecular biology 183, 192-201, 2018
342018
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