| 11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: a putative role in castration resistant prostate cancer? KH Storbeck, LM Bloem, D Africander, L Schloms, P Swart, AC Swart Molecular and cellular endocrinology 377 (1-2), 135-146, 2013 | 190 | 2013 |
| Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase P Swart, AC Swart, MR Waterman, RW Estabrook, JI Mason The Journal of Clinical Endocrinology & Metabolism 77 (1), 98-102, 1993 | 140 | 1993 |
| Formation of prothrombin converting activity HC Hemker, MP Esnouf, PW Hemker, ACW Swart, RG Macfarlane Nature 215 (5098), 248-251, 1967 | 125 | 1967 |
| The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: quantification of steroid intermediates and end products in H295R cells L Schloms, KH Storbeck, P Swart, WCA Gelderblom, AC Swart The Journal of steroid biochemistry and molecular biology 128 (3-5), 128-138, 2012 | 119 | 2012 |
| 11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione AC Swart, L Schloms, KH Storbeck, LM Bloem, T du Toit, JL Quanson, ... The Journal of steroid biochemistry and molecular biology 138, 132-142, 2013 | 107 | 2013 |
| Profiling adrenal 11β-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC2-MS/MS quantification of 11β-hydroxytestosterone, 11keto-testosterone … T du Toit, LM Bloem, JL Quanson, R Ehlers, AM Serafin, AC Swart The Journal of steroid biochemistry and molecular biology 166, 54-67, 2017 | 78 | 2017 |
| 11β-Hydroxyandrostenedione: downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways AC Swart, KH Storbeck Molecular and cellular endocrinology 408, 114-123, 2015 | 75 | 2015 |
| Discovery of Compound A–a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity E Lesovaya, A Yemelyanov, AC Swart, P Swart, G Haegeman, ... Oncotarget 6 (31), 30730, 2015 | 72 | 2015 |
| 11β-hydroxyandrostenedione returns to the steroid arena: biosynthesis, metabolism and function LM Bloem, KH Storbeck, L Schloms, AC Swart Molecules 18 (11), 13228-13244, 2013 | 65 | 2013 |
| Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas LM Bloem, KH Storbeck, P Swart, T du Toit, L Schloms, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 153, 80-92, 2015 | 59 | 2015 |
| A single amino acid residue, Ala 105, confers 16α-hydroxylase activity to human cytochrome P450 17α-hydroxylase/17, 20 lyase AC Swart, KH Storbeck, P Swart The Journal of steroid biochemistry and molecular biology 119 (3-5), 112-120, 2010 | 51 | 2010 |
| Cytochrome b5: novel roles in steroidogenesis KH Storbeck, AC Swart, P Goosen, P Swart Molecular and cellular endocrinology 371 (1-2), 87-99, 2013 | 48 | 2013 |
| Separation of blood coagulation factors II, VII, IX and X by cel filtration in the presence of Dextran blue ACW Swart, HC Hemker Biochimica et Biophysica Acta (BBA)-General Subjects 222 (3), 692-695, 1970 | 48 | 1970 |
| Functional expression and characterisation of human cytochrome P45017α in Pichia pastoris NW Kolar, AC Swart, JI Mason, P Swart Journal of biotechnology 129 (4), 635-644, 2007 | 47 | 2007 |
| Aspalathus linearis (Rooibos)–a functional food targeting cardiovascular disease C Smith, A Swart Food & function 9 (10), 5041-5058, 2018 | 44 | 2018 |
| The effect of Sutherlandia frutescens on steroidogenesis: confirming indigenous wisdom D Prevoo, C Smith, P Swart, AC Swart Endocrine research 30 (4), 745-751, 2004 | 44 | 2004 |
| Rooibos flavonoids inhibit the activity of key adrenal steroidogenic enzymes, modulating steroid hormone levels in H295R cells L Schloms, AC Swart Molecules 19 (3), 3681-3695, 2014 | 43 | 2014 |
| The influence of Sutherlandia frutescens on adrenal steroidogenic cytochrome P450 enzymes D Prevoo, P Swart, AC Swart Journal of ethnopharmacology 118 (1), 118-126, 2008 | 43 | 2008 |
| Biological activities of the shrub Salsola tuberculatiformis Botsch.: Contraceptive or stress alleviator? P Swart, AC Swart, A Louw, KJ van der Merwe Bioessays 25 (6), 612-619, 2003 | 43 | 2003 |
| Inefficient UGT-conjugation of adrenal 11β-hydroxyandrostenedione metabolites highlights C11-oxy C19 steroids as the predominant androgens in prostate cancer T Du Toit, AC Swart Molecular and cellular endocrinology 461, 265-276, 2018 | 37 | 2018 |
