| Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system AJ Dupuy, K Akagi, DA Largaespada, NG Copeland, NA Jenkins Nature 436 (7048), 221-226, 2005 | 574 | 2005 |
| Clonal selection drives genetic divergence of metastatic medulloblastoma X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ... Nature 482 (7386), 529-533, 2012 | 481 | 2012 |
| Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse LS Collier, CM Carlson, S Ravimohan, AJ Dupuy, DA Largaespada Nature 436 (7048), 272-276, 2005 | 467 | 2005 |
| Gene transfer into genomes of human cells by the sleeping beauty transposon system AM Geurts, Y Yang, KJ Clark, G Liu, Z Cui, AJ Dupuy, JB Bell, ... Molecular Therapy 8 (1), 108-117, 2003 | 441 | 2003 |
| A transposon-based genetic screen in mice identifies genes altered in colorectal cancer TK Starr, R Allaei, KAT Silverstein, RA Staggs, AL Sarver, TL Bergemann, ... Science 323 (5922), 1747-1750, 2009 | 392 | 2009 |
| Divergent clonal selection dominates medulloblastoma at recurrence AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ... Nature 529 (7586), 351-357, 2016 | 341 | 2016 |
| Leukaemia disease genes: large-scale cloning and pathway predictions J Li, H Shen, KL Himmel, AJ Dupuy, DA Largaespada, T Nakamura, ... Nature genetics 23 (3), 348-353, 1999 | 286 | 1999 |
| A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma VW Keng, A Villanueva, DY Chiang, AJ Dupuy, BJ Ryan, I Matise, ... Nature biotechnology 27 (3), 264-274, 2009 | 266 | 2009 |
| Mammalian germ-line transgenesis by transposition AJ Dupuy, K Clark, CM Carlson, S Fritz, AE Davidson, KM Markley, ... Proceedings of the National Academy of Sciences 99 (7), 4495-4499, 2002 | 257 | 2002 |
| Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma KM Mann, JM Ward, CCK Yew, A Kovochich, DW Dawson, MA Black, ... Proceedings of the National Academy of Sciences 109 (16), 5934-5941, 2012 | 233 | 2012 |
| Transposition and gene disruption in the male germline of the mouse AJ Dupuy, S Fritz, DA Largaespada genesis 30 (2), 82-88, 2001 | 232 | 2001 |
| Aberrant epithelial–mesenchymal Hedgehog signaling characterizes Barrett's metaplasia DH Wang, NJ Clemons, T Miyashita, AJ Dupuy, W Zhang, A Szczepny, ... Gastroenterology 138 (5), 1810-1822. e2, 2010 | 214 | 2010 |
| A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice AJ Dupuy, LM Rogers, J Kim, K Nannapaneni, TK Starr, P Liu, ... Cancer research 69 (20), 8150-8156, 2009 | 195 | 2009 |
| Transposon mutagenesis of the mouse germline CM Carlson, AJ Dupuy, S Fritz, KJ Roberg-Perez, CF Fletcher, ... Genetics 165 (1), 243-256, 2003 | 185 | 2003 |
| MicroRNA‐494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer L Lim, A Balakrishnan, N Huskey, KD Jones, M Jodari, R Ng, G Song, ... Hepatology 59 (1), 202-215, 2014 | 137 | 2014 |
| Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system LR Belur, JL Frandsen, AJ Dupuy, DH Ingbar, DA Largaespada, ... Molecular therapy 8 (3), 501-507, 2003 | 135 | 2003 |
| Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model EA Bard-Chapeau, AT Nguyen, AG Rust, A Sayadi, P Lee, BQ Chua, ... Nature genetics 46 (1), 24-32, 2014 | 125 | 2014 |
| Cell of origin strongly influences genetic selection in a mouse model of T-ALL KE Berquam-Vrieze, K Nannapaneni, BT Brett, L Holmfeldt, J Ma, ... Blood, The Journal of the American Society of Hematology 118 (17), 4646-4656, 2011 | 125 | 2011 |
| Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis JD Riordan, VW Keng, BR Tschida, TE Scheetz, JB Bell, ... PLoS genetics 9 (4), e1003441, 2013 | 121 | 2013 |
| Nucleotide bias observed with a short SELEX RNA aptamer library WH Thiel, T Bair, K Wyatt Thiel, JP Dassie, WM Rockey, CA Howell, ... Nucleic acid therapeutics 21 (4), 253-263, 2011 | 99 | 2011 |
