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Matshawandile Tukulula
Matshawandile Tukulula
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Year
Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities
M Tukulula, R Hayeshi, P Fonteh, D Meyer, A Ndamase, MT Madziva, ...
Pharmaceutical research 32, 2713-2726, 2015
602015
Synthesis and antiplasmodial and antimycobacterial evaluation of new nitroimidazole and nitroimidazooxazine derivatives
M Tukulula, RK Sharma, M Meurillon, A Mahajan, K Naran, D Warner, ...
ACS Medicinal Chemistry Letters 4 (1), 128-131, 2013
552013
In vitro evaluation of chloroquine-loaded and heparin surface-functionalized solid lipid nanoparticles
JO Muga, JW Gathirwa, M Tukulula, WGZO Jura
Malaria journal 17, 1-7, 2018
472018
The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives
M Tukulula, S Little, J Gut, PJ Rosenthal, B Wan, SG Franzblau, K Chibale
European journal of medicinal chemistry 57, 259-267, 2012
452012
Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents
M Tukulula, M Njoroge, GC Mugumbate, J Gut, PJ Rosenthal, S Barteau, ...
Bioorganic & medicinal chemistry 21 (17), 4904-4913, 2013
302013
Synthesis, characterization and optimization of poly(p-phenylenediamine)-based organoclay composite for Cr(IV) remediation
L Mdlalose, M Balogun, K Setshedi, M Tukulula, L Chimuka, A Chetty
Applied Clay Science 139, 72-80, 2017
272017
Functionalization of PLGA Nanoparticles with 1, 3-β-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages
M Tukulula, L Gouveia, P Paixao, R Hayeshi, B Naicker, A Dube
Pharmaceutical research 35, 1-11, 2018
252018
Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds
M Tukulula, M Njoroge, ET Abay, GC Mugumbate, L Wiesner, D Taylor, ...
ACS medicinal chemistry letters 4 (12), 1198-1202, 2013
222013
New thiazolidine‐2, 4‐dione derivatives combined with organometallic ferrocene: Synthesis, structure and antiparasitic activity
OO Oderinlo, M Tukulula, M Isaacs, HC Hoppe, D Taylor, VJ Smith, ...
Applied Organometallic Chemistry 32 (7), e4385, 2018
182018
New quinoline–urea–benzothiazole hybrids as promising antitubercular agents: synthesis, in vitro antitubercular activity, cytotoxicity studies, and in silico ADME profiling
R Moodley, C Mashaba, GH Rakodi, NB Ncube, MV Maphoru, ...
Pharmaceuticals 15 (5), 576, 2022
142022
Indolizine Studies, Part 5: Indolizine-2-carboxamides as Potential HIV-1 Protease Inhibitors[ ]
M Tukulula, R Klein, PT Kaye
Synthetic Communications® 40 (13), 2018-2028, 2010
142010
Strong base-or acid-mediated chemoselectivity shifts in the synthesis of 2H-chromene or coumarin derivatives from common Baylis-Hillman adducts
TO Olomola, M Tukulula, R Klein, PT Kaye
Tetrahedron 71 (29), 4868-4873, 2015
82015
A sustainable molybdenum oxide loaded on zirconia (MoO3/ZrO2) catalysed multicomponent reaction to synthesise novel dihydropyridines
NP Hadebe, N Kerru, M Tukulula, SB Jonnalagadda
Sustainable Chemistry and Pharmacy 25, 100578, 2022
72022
Synthesis and in vitro antiprotozoan evaluation of 4-/8-aminoquinoline-based lactams and tetrazoles
M Tukulula, S Louw, M Njoroge, K Chibale
Molecules 25 (24), 5941, 2020
32020
The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic …
ET Abay, JH van der Westhuizen, KJ Swart, L Gibhard, M Tukulula, ...
Malaria journal 13, 1-13, 2014
32014
Hydrazone‐Tethered 5‐(Pyridin‐4‐yl)‐4H‐1,2,4‐triazole‐3‐thiol Hybrids: Synthesis, Characterisation, in silico ADME Studies, and in vitro Antimycobacterial …
OO Oderinlo, A Jordaan, R Seldon, M Isaacs, HC Hoppe, DF Warner, ...
ChemMedChem 18 (6), e202200572, 2023
12023
Discovery of Novel Thiazolidinedione-Derivatives with Multi-Modal Antidiabetic Activities In Vitro and In Silico
C Arineitwe, O Oderinlo, M Tukulula, S Khanye, A Khathi, N Sibiya
International Journal of Molecular Sciences 24 (3), 3024, 2023
12023
Synthesis, characterization, in vitro antimycobacterial and cytotoxicity evaluation, DFT calculations, molecular docking and ADME studies of new isomeric benzimidazole-1, 2, 3 …
NTP Nyoni, NB Ncube, MX Kubheka, NP Mkhwanazi, S Senzani, T Singh, ...
Bioorganic Chemistry 141, 106904, 2023
2023
A critical analysis of the binding pocket of Plasmodium falciparum Phosphatidylinositol‐4‐kinase enzyme
NB Ncube, KK Govender, M Tukulula
ChemistrySelect 8 (43), e202302189, 2023
2023
Synthesis, stereochemistry and in vitro STD NMR and in silico HIV-1 PR enzyme-binding potential of MBH-derived inhibitors
M Tukulula, IA Olasupo, GC Mugumbate, KA Lobb, R Klein, Y Sayed, ...
Journal of Molecular Structure 1268, 133716, 2022
2022
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