| Roles of F-box proteins in cancer Z Wang, P Liu, H Inuzuka, W Wei Nature reviews Cancer 14 (4), 233-247, 2014 | 487 | 2014 |
| CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 B Bartkowiak, P Liu, HP Phatnani, NJ Fuda, JJ Cooper, DH Price, ... Genes & development 24 (20), 2303-2316, 2010 | 447 | 2010 |
| PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ... Cancer discovery 5 (11), 1194-1209, 2015 | 396 | 2015 |
| Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus P Liu, M Begley, W Michowski, H Inuzuka, M Ginzberg, D Gao, P Tsou, ... Nature 508 (7497), 541-545, 2014 | 378 | 2014 |
| Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis P Liu, W Gan, H Inuzuka, AS Lazorchak, D Gao, O Arojo, D Liu, L Wan, ... Nature cell biology 15 (11), 1340-1350, 2013 | 300 | 2013 |
| Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4 X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ... Nature medicine 23 (9), 1063-1071, 2017 | 277 | 2017 |
| mTOR drives its own activation via SCFβTrCP-dependent degradation of the mTOR inhibitor DEPTOR D Gao, H Inuzuka, MKM Tan, H Fukushima, JW Locasale, P Liu, L Wan, ... Molecular cell 44 (2), 290-303, 2011 | 268 | 2011 |
| Therapeutic implications for overcoming radiation resistance in cancer therapy BM Kim, Y Hong, S Lee, P Liu, JH Lim, YH Lee, TH Lee, KT Chang, ... International journal of molecular sciences 16 (11), 26880-26913, 2015 | 228 | 2015 |
| SPOP promotes ubiquitination and degradation of the ERG oncoprotein to suppress prostate cancer progression W Gan, X Dai, A Lunardi, Z Li, H Inuzuka, P Liu, S Varmeh, J Zhang, ... Molecular cell 59 (6), 917-930, 2015 | 201 | 2015 |
| mTOR signaling in tumorigenesis K Xu, P Liu, W Wei Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (2), 638-654, 2014 | 198 | 2014 |
| Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer L Yu, J Wei, P Liu Seminars in cancer biology 85, 69-94, 2022 | 187 | 2022 |
| pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner J Guo, AA Chakraborty, P Liu, W Gan, X Zheng, H Inuzuka, B Wang, ... Science 353 (6302), 929-932, 2016 | 180 | 2016 |
| cis-Proline-mediated Ser (P) 5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72 JW Werner-Allen, CJ Lee, P Liu, NI Nicely, S Wang, AL Greenleaf, P Zhou Journal of Biological Chemistry 286 (7), 5717-5726, 2011 | 160 | 2011 |
| Structural basis of nucleosome-dependent cGAS inhibition JA Boyer, CJ Spangler, JD Strauss, AP Cesmat, P Liu, RK McGinty, ... Science 370 (6515), 450-454, 2020 | 155 | 2020 |
| TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling B Wang, Z Jie, D Joo, A Ordureau, P Liu, W Gan, J Guo, J Zhang, BJ North, ... Nature 545 (7654), 365-369, 2017 | 153 | 2017 |
| Skp2: a novel potential therapeutic target for prostate cancer Z Wang, D Gao, H Fukushima, H Inuzuka, P Liu, L Wan, FH Sarkar, W Wei Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1825 (1), 11-17, 2012 | 138 | 2012 |
| Cdc20: a potential novel therapeutic target for cancer treatment Z Wang, L Wan, J Zhong, H Inuzuka, P Liu, FH Sarkar, W Wei Current pharmaceutical design 19 (18), 3210-3214, 2013 | 126 | 2013 |
| Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+ liver cancer initiating cells by suppressing negative regulators of β-catenin signaling B 3. Lei, Z.J., Wang, J., Xiao, H.L., Guo, Y., Wang, T., Li, Q., Liu, L ... Oncogene 34 (24), 3188-3198, 2015 | 115 | 2015 |
| AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions J Guo, X Dai, B Laurent, N Zheng, W Gan, J Zhang, A Guo, M Yuan, P Liu, ... Nature cell biology 21 (2), 226-237, 2019 | 113 | 2019 |
| Inhibition of Rb phosphorylation leads to mTORC2-mediated activation of Akt J Zhang, K Xu, P Liu, Y Geng, B Wang, W Gan, J Guo, F Wu, YR Chin, ... Molecular cell 62 (6), 929-942, 2016 | 104 | 2016 |
