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Gina Leisching
Gina Leisching
Senior Research Fellow
Verified email at tcd.ie
Title
Cited by
Cited by
Year
The association of OASL and type I interferons in the pathogenesis and survival of intracellular replicating bacterial species
G Leisching, I Wiid, B Baker
Frontiers in cellular and infection microbiology 7, 196, 2017
532017
Comparison of human monocyte derived macrophages and THP1-like macrophages as in vitro models for M. tuberculosis infection
A Madhvi, H Mishra, GR Leisching, PZ Mahlobo, B Baker
Comparative immunology, microbiology and infectious diseases 67, 101355, 2019
502019
Bcl-2 confers survival in cisplatin treated cervical cancer cells: circumventing cisplatin dose-dependent toxicity and resistance
G Leisching, B Loos, M Botha, AM Engelbrecht
Journal of translational medicine 13, 1-8, 2015
502015
OAS1, OAS2 and OAS3 restrict intracellular M. tb replication and enhance cytokine secretion
G Leisching, V Cole, AT Ali, B Baker
International journal of infectious diseases 80, S77-S84, 2019
482019
The host response to a clinical MDR mycobacterial strain cultured in a detergent-free environment: a global transcriptomics approach
G Leisching, RD Pietersen, V Mpongoshe, C Van Heerden, P Van Helden, ...
PLoS One 11 (4), e0153079, 2016
382016
The role of mTOR during cisplatin treatment in an in vitro and ex vivo model of cervical cancer
GR Leisching, B Loos, MH Botha, AM Engelbrecht
Toxicology 335, 72-78, 2015
382015
RNAseq reveals hypervirulence-specific host responses to M. tuberculosis infection
G Leisching, RD Pietersen, C van Heerden, P van Helden, I Wiid, B Baker
Virulence 8 (6), 848-858, 2017
292017
OAS1, 2, and 3: significance during active tuberculosis?
G Leisching, I Wiid, B Baker
The Journal of infectious diseases 217 (10), 1517-1521, 2018
272018
Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis
C Maoldomhnaigh, DJ Cox, JJ Phelan, M Mitermite, DM Murphy, ...
Frontiers in Immunology 12, 663695, 2021
262021
Tween 80 induces a carbon flux rerouting in Mycobacterium tuberculosis
RD Pietersen, I Du Preez, M van Reenen, D Beukes, G Leisching, ...
Journal of microbiological methods 170, 105795, 2020
252020
A nontoxic concentration of cisplatin induces autophagy in cervical cancer: selective cancer cell death with autophagy inhibition as an adjuvant treatment
G Leisching, B Loos, M Botha, AM Engelbrecht
International Journal of Gynecologic Cancer 25 (3), 2015
252015
Virulence, biochemistry, morphology and host-interacting properties of detergent-free cultured mycobacteria: An update
G Leisching, RD Pietersen, I Wiid, B Baker
Tuberculosis 100, 53-60, 2016
242016
Susceptibility to tuberculosis is associated with PI3K-dependent increased mobilization of neutrophils
GR Leisching
Frontiers in Immunology 9, 1669, 2018
212018
Sutherlandia frutescens treatment induces apoptosis and modulates the PI3-kinase pathway in colon cancer cells
G Leisching, B Loos, T Nell, AM Engelbrecht
South African Journal of Botany 100, 20-26, 2015
192015
2′-5′-Oligoadenylate synthetase-like protein inhibits intracellular M. tuberculosis replication and promotes proinflammatory cytokine secretion
G Leisching, A Ali, V Cole, B Baker
Molecular immunology 118, 73-78, 2020
172020
Distinct host-immune response toward species related intracellular mycobacterial killing: A transcriptomic study
A Madhvi, H Mishra, NN Chegou, G Tromp, CJ Van Heerden, ...
Virulence 11 (1), 170-182, 2020
112020
Mitochondrial bioenergetic changes in systemic lupus erythematosus immune cell subsets: Contributions to pathogenesis and clinical applications
AS Yennemadi, J Keane, G Leisching
Lupus 32 (5), 603-611, 2023
72023
Immunoglobulin profile and B‐cell frequencies are altered with changes in the cellular microenvironment independent of the stimulation conditions
DK Moore, GR Leisching, CI Snyders, A Gutschmidt, IC van Rensburg, ...
Immunity, Inflammation and Disease 8 (3), 458-467, 2020
42020
Chronic IFNα treatment induces leukopoiesis, increased plasma succinate and immune cell metabolic rewiring
AS Yennemadi, G Jameson, M Glass, C De Pasquale, J Keane, M Bianchi, ...
Cellular Immunology 390, 104741, 2023
32023
Bystander Macrophage Metabolic Shift after Mycobacterium tuberculosis Infection
G Leisching, J Keane
American Journal of Respiratory Cell and Molecular Biology 63 (6), 863-865, 2020
32020
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Articles 1–20