| Negative regulation of toll-like receptor-mediated immune responses FY Liew, D Xu, EK Brint, LAJ O'Neill Nature Reviews Immunology 5 (6), 446-458, 2005 | 1900 | 2005 |
| Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction KA Fitzgerald, EM Palsson-McDermott, AG Bowie, CA Jefferies, ... Nature 413 (6851), 78-83, 2001 | 1690 | 2001 |
| ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance EK Brint, D Xu, H Liu, A Dunne, ANJ McKenzie, LAJ O'Neill, FY Liew Nature immunology 5 (4), 373-379, 2004 | 676 | 2004 |
| Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor κB activation by Toll-like receptor 4 CA Jefferies, S Doyle, C Brunner, A Dunne, E Brint, C Wietek, E Walch, ... Journal of Biological Chemistry 278 (28), 26258-26264, 2003 | 398 | 2003 |
| Differential expression of toll-like receptors in patients with irritable bowel syndrome EK Brint, J MacSharry, A Fanning, F Shanahan, EMM Quigley Official journal of the American College of Gastroenterology| ACG 106 (2 …, 2011 | 275 | 2011 |
| IL-1 family members in cancer; two sides to every story KJ Baker, A Houston, E Brint Frontiers in immunology 10, 459981, 2019 | 259 | 2019 |
| Trif-related adapter molecule is phosphorylated by PKCε during Toll-like receptor 4 signaling AF McGettrick, EK Brint, EM Palsson-McDermott, DC Rowe, ... Proceedings of the National Academy of Sciences 103 (24), 9196-9201, 2006 | 168 | 2006 |
| Identification of TLR10 as a key mediator of the inflammatory response to Listeria monocytogenes in intestinal epithelial cells and macrophages T Regan, K Nally, R Carmody, A Houston, F Shanahan, J Macsharry, ... The Journal of Immunology 191 (12), 6084-6092, 2013 | 166 | 2013 |
| Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-κB activation by Toll-like receptor (TLR)-2 and TLR4 A Mansell, E Brint, JA Gould, LA O'Neill, PJ Hertzog Journal of Biological Chemistry 279 (36), 37227-37230, 2004 | 165 | 2004 |
| Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL JA Khan, EK Brint, LAJ O'Neill, L Tong Journal of Biological Chemistry 279 (30), 31664-31670, 2004 | 151 | 2004 |
| Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions NP Hyland, EMM Quigley, E Brint World journal of gastroenterology: WJG 20 (27), 8859, 2014 | 135 | 2014 |
| IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation SE Russell, RM Horan, AM Stefanska, A Carey, G Leon, M Aguilera, ... Mucosal immunology 9 (5), 1193-1204, 2016 | 131 | 2016 |
| Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2: a role for Jun N-terminal kinase in IL-4 induction EK Brint, KA Fitzgerald, P Smith, AJ Coyle, JC Gutierrez-Ramos, ... Journal of Biological Chemistry 277 (51), 49205-49211, 2002 | 107 | 2002 |
| An antitumorigenic role for the IL-33 receptor, ST2L, in colon cancer C O'donnell, A Mahmoud, J Keane, C Murphy, D White, S Carey, ... British journal of cancer 114 (1), 37-43, 2016 | 91 | 2016 |
| Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome DP McKernan, A Nolan, EK Brint, SM O'Mahony, NP Hyland, JF Cryan, ... PloS one 4 (12), e8226, 2009 | 84 | 2009 |
| Differential expression of key regulators of Toll-like receptors in ulcerative colitis and Crohn's disease: a role for Tollip and peroxisome proliferator-activated receptor gamma? P Fernandes, J MacSharry, T Darby, A Fanning, F Shanahan, A Houston, ... Clinical & Experimental Immunology 183 (3), 358-368, 2016 | 78 | 2016 |
| Life in the Fas lane: differential outcomes of Fas signaling E Brint, G O’Callaghan, A Houston Cellular and molecular life sciences 70, 4085-4099, 2013 | 70 | 2013 |
| Wounds that heal and wounds that don’t− The role of the IL-33/ST2 pathway in tissue repair and tumorigenesis NL Millar, C O’Donnell, IB McInnes, E Brint Seminars in Cell & Developmental Biology 61, 41-50, 2017 | 50 | 2017 |
| Bcl-3 deficiency protects against dextran-sodium sulphate-induced colitis in the mouse C O'Carroll, G Moloney, G Hurley, S Melgar, E Brint, K Nally, RJ Nibbs, ... Clinical & Experimental Immunology 173 (2), 332-342, 2013 | 30 | 2013 |
| IL-36 cytokines in inflammatory and malignant diseases: not the new kid on the block anymore J Byrne, K Baker, A Houston, E Brint Cellular and Molecular Life Sciences 78 (17-18), 6215-6227, 2021 | 25 | 2021 |
