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| Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis RA Hlady, RL Tiedemann, W Puszyk, I Zendejas, LR Roberts, JH Choi, ... Oncotarget 5 (19), 9425, 2014 | 90 | 2014 |
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| Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues D Zhou, BM Alver, S Li, RA Hlady, JJ Thompson, MA Schroeder, JH Lee, ... Genome biology 19, 1-25, 2018 | 88 | 2018 |
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| Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis RA Hlady, S Novakova, J Opavska, D Klinkebiel, SL Peters, J Bies, ... The Journal of clinical investigation 122 (1), 163-177, 2012 | 73 | 2012 |
| Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas SL Peters, RA Hlady, J Opavska, D Klinkebiel, S Novakova, LM Smith, ... Molecular and cellular biology 33 (21), 4321-4333, 2013 | 69 | 2013 |
| Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma RL Tiedemann, RA Hlady, PD Hanavan, DF Lake, R Tibes, JH Lee, ... Oncotarget 7 (2), 1927, 2016 | 55 | 2016 |
| High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver D Zhou, RA Hlady, MJ Schafer, TA White, C Liu, JH Choi, JD Miller, ... Epigenetics 12 (1), 55-69, 2017 | 49 | 2017 |
| Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis SL Peters, RA Hlady, J Opavska, D Klinkebiel, SJ Pirruccello, GA Talmon, ... Leukemia 28 (5), 1138-1142, 2014 | 47 | 2014 |
| Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome RL Tiedemann, EL Putiri, JH Lee, RA Hlady, K Kashiwagi, T Ordog, ... Cell reports 9 (4), 1554-1566, 2014 | 42 | 2014 |
| Dnmt3a is a haploinsufficient tumor suppressor in CD8+ peripheral T cell lymphoma SL Haney, GM Upchurch, J Opavska, D Klinkebiel, RA Hlady, S Roy, ... PLoS genetics 12 (9), e1006334, 2016 | 40 | 2016 |
| DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma Y Zheng, RA Hlady, BT Joyce, KD Robertson, C He, DR Nannini, ... Clinical Epigenetics 11, 1-13, 2019 | 37 | 2019 |
| Promoter hypomethylation and expression is conserved in mouse chronic lymphocytic leukemia induced by decreased or inactivated Dnmt3a SL Haney, GM Upchurch, J Opavska, D Klinkebiel, RA Hlady, A Suresh, ... Cell Reports 15 (6), 1190-1201, 2016 | 37 | 2016 |
| Initiation of aberrant DNA methylation patterns and heterogeneity in precancerous lesions of human hepatocellular cancer RA Hlady, D Zhou, W Puszyk, LR Roberts, C Liu, KD Robertson Epigenetics 12 (3), 215-225, 2017 | 34 | 2017 |
| Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions P Nowialis, K Lopusna, J Opavska, SL Haney, A Abraham, P Sheng, ... Nature communications 10 (1), 4374, 2019 | 33 | 2019 |
| Perinatal nutritional reprogramming of the epigenome promotes subsequent development of nonalcoholic steatohepatitis LHG Sanchez, K Tomita, Q Guo, K Furuta, H Alhuwaish, P Hirsova, ... Hepatology Communications 2 (12), 1493-1512, 2018 | 30 | 2018 |
| Genetic and epigenetic heterogeneity in normal liver homeostasis and its implications for liver disease and hepatocellular cancer RA Hlady, KD Robertson Seminars in liver disease 38 (01), 041-050, 2018 | 29 | 2018 |
| Alpha‐1 antitrypsin deficiency liver disease, mutational homogeneity modulated by epigenetic heterogeneity with links to obesity L Wang, GW Marek III, RA Hlady, RT Wagner, X Zhao, VC Clark, AX Fan, ... Hepatology 70 (1), 51-66, 2019 | 26 | 2019 |
