| Binuclear metal centers in plant purple acid phosphatases: Fe–Mn in sweet potato and Fe–Zn in soybean G Schenk, Y Ge, LE Carrington, CJ Wynne, IR Searle, BJ Carroll, ... Archives of Biochemistry and Biophysics 370 (2), 183-189, 1999 | 220 | 1999 |
| Binding of released Bim to Mcl-1 is a mechanism of intrinsic resistance to ABT-199 which can be overcome by combination with daunorubicin or cytarabine in AML cells X Niu, J Zhao, J Ma, C Xie, H Edwards, G Wang, JT Caldwell, S Xiang, ... Clinical Cancer Research 22 (17), 4440-4451, 2016 | 209 | 2016 |
| Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib ME Irwin, KL Mueller, N Bohin, Y Ge, JL Boerner Journal of cellular physiology 226 (9), 2316-2328, 2011 | 202 | 2011 |
| Identification of mammalian-like purple acid phosphatases in a wide range of plants G Schenk, LW Guddat, Y Ge, LE Carrington, DA Hume, S Hamilton, ... Gene 250 (1-2), 117-125, 2000 | 186 | 2000 |
| The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group A Larson Gedman, Q Chen, S Kugel Desmoulin, Y Ge, K LaFiura, ... Leukemia 23 (8), 1417-1425, 2009 | 173 | 2009 |
| A delicate balance–The BCL-2 family and its role in apoptosis, oncogenesis, and cancer therapeutics T Knight, D Luedtke, H Edwards, JW Taub, Y Ge Biochemical pharmacology 162, 250-261, 2019 | 157 | 2019 |
| Down syndrome and malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathology AC Xavier, Y Ge, JW Taub The Journal of molecular diagnostics: JMD 11 (5), 371, 2009 | 144 | 2009 |
| High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia JW Taub, MA Konrad, Y Ge, JM Naber, JS Scott, LH Matherly, ... Blood, The Journal of the American Society of Hematology 99 (8), 2992-2996, 2002 | 143 | 2002 |
| Down syndrome, drug metabolism and chromosome 21 JW Taub, Y Ge Pediatric blood & cancer 44 (1), 33-39, 2004 | 139 | 2004 |
| Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy JL Carter, K Hege, J Yang, HA Kalpage, Y Su, H Edwards, M Hüttemann, ... Signal transduction and targeted therapy 5 (1), 288, 2020 | 136 | 2020 |
| The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation M Li, JY Zhou, Y Ge, LH Matherly, GS Wu Journal of Biological Chemistry 278 (42), 41059-41068, 2003 | 136 | 2003 |
| Inhibition of Mcl-1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells DA Luedtke, X Niu, Y Pan, J Zhao, S Liu, H Edwards, K Chen, H Lin, ... Signal transduction and targeted therapy 2 (1), 1-9, 2017 | 135 | 2017 |
| Inhibition of Bcl-2 synergistically enhances the antileukemic activity of midostaurin and gilteritinib in preclinical models of FLT3-mutated acute myeloid leukemia J Ma, S Zhao, X Qiao, T Knight, H Edwards, L Polin, J Kushner, SH Dzinic, ... Clinical Cancer Research 25 (22), 6815-6826, 2019 | 128 | 2019 |
| GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with acute megakaryocytic leukemia Y Ge, ML Stout, DA Tatman, TL Jensen, S Buck, RL Thomas, ... Journal of the National Cancer Institute 97 (3), 226-231, 2005 | 128 | 2005 |
| Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome JW Taub, G Mundschau, Y Ge, JM Poulik, F Qureshi, T Jensen, SJ James, ... Blood 104 (5), 1588-1589, 2004 | 113 | 2004 |
| Acute myeloid leukemia cells harboring MLL fusion genes or with the acute promyelocytic leukemia phenotype are sensitive to the Bcl-2-selective inhibitor ABT-199 X Niu, G Wang, Y Wang, JT Caldwell, H Edwards, C Xie, JW Taub, C Li, ... Leukemia 28 (7), 1557-1560, 2014 | 107 | 2014 |
| Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia Y Ge, AA Dombkowski, KM LaFiura, D Tatman, RS Yedidi, ML Stout, ... Blood 107 (4), 1570-1581, 2006 | 107 | 2006 |
| The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines Y Ge, TL Jensen, ML Stout, RM Flatley, PJ Grohar, Y Ravindranath, ... Cancer research 64 (2), 728-735, 2004 | 104 | 2004 |
| Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51 C Xie, C Drenberg, H Edwards, JT Caldwell, W Chen, H Inaba, X Xu, ... PloS one 8 (11), e79106, 2013 | 101 | 2013 |
| Improved outcomes for myeloid leukemia of Down syndrome: a report from the Children’s Oncology Group AAML0431 trial JW Taub, JN Berman, JK Hitzler, AD Sorrell, NJ Lacayo, K Mast, D Head, ... Blood, The Journal of the American Society of Hematology 129 (25), 3304-3313, 2017 | 96 | 2017 |
