Exploitation of a novel phenothiazine derivative for its anti-cancer activities in malignant glioblastoma SI Omoruyi, OE Ekpo, DM Semenya, A Jardine, S Prince Apoptosis 25 (3), 261-274, 2020 | 41 | 2020 |
GRP78/BIP/HSPA5 as a therapeutic target in models of Parkinson’s disease: a mini review AB Enogieru, SI Omoruyi, DC Hiss, OE Ekpo Advances in Pharmacological and Pharmaceutical Sciences 2019, 2019 | 39 | 2019 |
Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease I Denya, SF Malan, AB Enogieru, SI Omoruyi, OE Ekpo, E Kapp, FT Zindo, ... MedChemComm 9 (2), 357-370, 2018 | 31 | 2018 |
Long‑term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats O Akinrinmade, S Omoruyi, D Dietrich, O Ekpo Acta neurobiologiae experimentalis 77 (1), 94-105, 2017 | 28 | 2017 |
Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents E Kapp, H Visser, SL Sampson, SF Malan, EM Streicher, GB Foka, ... Molecules 22 (10), 1644, 2017 | 27 | 2017 |
Cytotoxic activities of selected plants of the family Amaryllidaceae on brain tumour cell lines SI Omoruyi, TS Kangwa, AS Ibrakaw, CN Cupido, JL Marnewick, OE Ekpo, ... South African Journal of Botany 136, 118-125, 2021 | 22 | 2021 |
Design, synthesis and evaluation of pentacycloundecane and hexacycloundecane propargylamine derivatives as multifunctional neuroprotective agents FT Zindo, SF Malan, SI Omoruyi, AB Enogieru, OE Ekpo, J Joubert European journal of medicinal chemistry 163, 83-94, 2019 | 20 | 2019 |
The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus AAH Akinfenwa A. Omolaja, Brendon Pearce, Sylvester I. Omoruyi, Jelili A ... Surfaces and Interfaces 25, 101251, 2021 | 17 | 2021 |
Design, synthesis, and evaluation of 3, 7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents SC Mzezewa, SI Omoruyi, LS Zondagh, SF Malan, OE Ekpo, J Joubert Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1606-1620, 2021 | 16 | 2021 |
In vitro neuroprotective potential of Clivia miniata and Nerine humilis (Amaryllidaceae) in MPP+-induced neuronal toxicity in SH-SY5Y neuroblastoma cells SI Omoruyi, J Delport, TS Kangwa, AS Ibrakaw, CN Cupido, OE Ekpo, ... South African Journal of Botany 136, 110-117, 2021 | 16 | 2021 |
Aqueous leaf extract of Sutherlandia frutescens attenuates ROS-induced apoptosis and loss of mitochondrial membrane potential in MPP+-treated SH-SY5Y cells AB Enogieru, SI Omoruyi, OE Ekpo Tropical Journal of Pharmaceutical Research 19 (3), 549-555, 2020 | 16 | 2020 |
Open and rearranged norbornane derived polycyclic cage molecules as potential neuroprotective agents through attenuation of MPP+-and calcium overload-induced excitotoxicity in … AO Egunlusi, SF Malan, SI Omoruyi, OE Ekpo, VA Palchykov, J Joubert European Journal of Medicinal Chemistry 204, 112617, 2020 | 13 | 2020 |
Potential antiparkinsonian agents derived from South African medicinal plants AB Enogieru, SI Omoruyi, DC Hiss, OE Ekpo Journal of herbal medicine 13, 1-7, 2018 | 13 | 2018 |
Antioxidant and apoptosis-inhibition potential of Carpobrotus edulis in a model of parkinson’s disease AB Enogieru, SI Omoruyi, OE Ekpo Journal of African Association of Physiological Sciences 6 (2), 126-135, 2018 | 13 | 2018 |
Extracts of Hunteria umbellata reverses the effect of streptozotocin-induced pancreatic islet-cell destruction O Momodu, A Enogieru, S Omoruyi, FAE OmIniabohs J Exp Clin Anat 13 (12), 66-73, 2014 | 11 | 2014 |
Neuroprotective Activities of Boophone haemanthoides (Amaryllidaceae) Extract and Its Chemical Constituents AS Ibrakaw, SI Omoruyi, OE Ekpo, AA Hussein Molecules 25 (22), 5376, 2020 | 10 | 2020 |
Preliminary investigation of the neuroprotective potentials of Crossyne guttata in MPP+-induced toxicity in SH-SY5Y SI Omoruyi, AB Enogieru, AA Hussein, OE Ekpo Journal of African Association of Physiological Sciences 7 (2), 138-144, 2019 | 10 | 2019 |
Exploration of Aqueous Phyllanthus amarus Leaf Extract as a Protective Agent in Mercury Chloride-Exposed Wistar Rats: A Neurobehavioural Study AB Enogieru, SI Omoruyi Journal of Applied Sciences and Environmental Management 26 (4), 629-637, 2022 | 9 | 2022 |
Changes in Biochemical Markers of Kidney Function and Antioxidant Status of Diabetic Rats treated with Aqueous Leaf Extracts of Ficus exasperata (Vahl) AB Enogieru, OI Momodu, SI Omoruyi, FAE Om'iniabohs African Journal of Biomedical Research 18 (1), 61-67, 2015 | 9 | 2015 |
Neuroprotective Activities of Crossyne flava Bulbs and Amaryllidaceae Alkaloids: Implications for Parkinson’s Disease SI Omoruyi, AS Ibrakaw, OE Ekpo, JS Boatwright, CN Cupido, AA Hussein Molecules 26 (13), 3990, 2021 | 8 | 2021 |