β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer SP Tenbaum, P Ordóñez-Morán, I Puig, I Chicote, O Arqués, S Landolfi, ... Nature medicine 18 (6), 892-901, 2012 | 420 | 2012 |
p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation JJ Ventura, S Tenbaum, E Perdiguero, M Huth, C Guerra, M Barbacid, ... Nature genetics 39 (6), 750-758, 2007 | 369 | 2007 |
Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily U Dressel, D Thormeyer, B Altincicek, A Paululat, M Eggert, S Schneider, ... Molecular and Cellular Biology 19 (5), 3383-3394, 1999 | 239 | 1999 |
Thyroid hormone receptor β1 acts as a potent suppressor of tumor invasiveness and metastasis O Martínez-Iglesias, S Garcia-Silva, SP Tenbaum, J Regadera, F Larcher, ... Cancer research 69 (2), 501-509, 2009 | 177 | 2009 |
Tankyrase inhibition blocks Wnt/β-catenin pathway and reverts resistance to PI3K and AKT inhibitors in the treatment of colorectal cancer O Arqués, I Chicote, I Puig, SP Tenbaum, G Argilés, R Dienstmann, ... Clinical cancer research 22 (3), 644-656, 2016 | 167 | 2016 |
Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF P Andreu-Pérez, R Esteve-Puig, C de Torre-Minguela, M López-Fauqued, ... Science signaling 4 (190), ra58-ra58, 2011 | 161 | 2011 |
Nuclear receptors: structure, function and involvement in disease S Tenbaum, A Baniahmad The international journal of biochemistry & cell biology 29 (12), 1325-1341, 1997 | 159 | 1997 |
Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes A Herrero, A Pinto, P Colón-Bolea, B Casar, M Jones, L Agudo-Ibáñez, ... Cancer cell 28 (2), 170-182, 2015 | 146 | 2015 |
Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita B Altincicek, SP Tenbaum, U Dressel, D Thormeyer, R Renkawitz, ... Journal of Biological Chemistry 275 (11), 7662-7667, 2000 | 131 | 2000 |
TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence I Puig, SP Tenbaum, I Chicote, O Arques, J Martinez-Quintanilla, ... The Journal of clinical investigation 128 (9), 3887-3905, 2018 | 98 | 2018 |
A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells I Puig, I Chicote, SP Tenbaum, O Arqués, JR Herance, JD Gispert, ... Clinical Cancer Research 19 (24), 6787-6801, 2013 | 95 | 2013 |
BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways L Jubierre, A Soriano, L Planells-Ferrer, L París-Coderch, SP Tenbaum, ... Oncogene 35 (39), 5179-5190, 2016 | 85 | 2016 |
Standardized relative quantification of immunofluorescence tissue staining S Tenbaum, HG Palmer, O Arqués, I Chicote, I Puig | 55 | 2012 |
The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF I Arozarena, DS Aaronson, D Matallanas, V Sanz, N Ajenjo, SP Tenbaum, ... Journal of Biological Chemistry 275 (34), 26441-26448, 2000 | 54 | 2000 |
ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment M Pérez-Alea, K McGrail, S Sánchez-Redondo, B Ferrer, G Fournet, ... Oncogene 36 (41), 5695-5708, 2017 | 53 | 2017 |
Activation of the human immunodeficiency virus type I long terminal repeat by 1α, 25-dihydroxyvitamin D3 J Nevado, SP Tenbaum, AI Castillo, A Sánchez-Pacheco, A Aranda Journal of molecular endocrinology 38 (6), 587-601, 2007 | 43 | 2007 |
Complete remission of palmoplantar psoriasis through Helicobacter pylori eradication: a case report AM Hübner, SP Tenbaum Clinical and experimental dermatology 33 (3), 339-340, 2008 | 39 | 2008 |
Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain SP Tenbaum, S Juenemann, T Schlitt, J Bernal, R Renkawitz, A Muñoz, ... Developmental biology 254 (1), 149-160, 2003 | 35 | 2003 |
SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer P Ordóñez-Morán, A Irmisch, A Barbáchano, I Chicote, S Tenbaum, ... Oncogene 33 (15), 1975-1985, 2014 | 32 | 2014 |
hSrb7, an essential human Mediator component, acts as a coactivator for the thyroid hormone receptor J Nevado, SP Tenbaum, A Aranda Molecular and cellular endocrinology 222 (1-2), 41-51, 2004 | 23 | 2004 |