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RICHARD MBI BETECK
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Recent progress in the development of anti-malarial quinolones
RM Beteck, FJ Smit, RK Haynes, DD N’Da
Malaria journal 13, 1-10, 2014
942014
Antimalarial application of quinones: A recent update
OPS Patel, RM Beteck, LJ Legoabe
European Journal of Medicinal Chemistry 210, 113084, 2021
642021
Chemical classes presenting novel antituberculosis agents currently in different phases of drug development: A 2010–2020 review
KT Angula, LJ Legoabe, RM Beteck
Pharmaceuticals 14 (5), 461, 2021
402021
Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research
OPS Patel, RM Beteck, LJ Legoabe
European journal of medicinal chemistry 213, 113193, 2021
352021
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites
RM Beteck, R Seldon, D Coertzen, ME van der Watt, J Reader, ...
COMMUNICATIONS CHEMISTRY- NATURE 1, 62, 2018
332018
Quinolone-isoniazid hybrids: Synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation
RM Beteck, R Seldon, A Jordaan, DF Warner, HC Hoppe, D Laming, ...
Medchemcomm 10 (2), 326-331, 2019
282019
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective
OPS Patel, OJ Jesumoroti, LJ Legoabe, RM Beteck
European Journal of Medicinal Chemistry 210, 112994, 2021
232021
Cinnamoyl-oxaborole amides: Synthesis and their in vitro biological activity
M Gumbo, RM Beteck, T Mandizvo, R Seldon, DF Warner, HC Hoppe, ...
Molecules 23 (8), 2038, 2018
202018
Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities
RM Beteck, D Coertzen, FJ Smit, LM Birkholtz, RK Haynes, DD N’Da
Bioorganic & Medicinal Chemistry Letters 26 (13), 3006-3009, 2016
202016
Quinolone: a versatile therapeutic compound class
PS Dube, LJ Legoabe, RM Beteck
Molecular Diversity 27 (3), 1501-1526, 2023
192023
New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis
RM Beteck, R Seldon, A Jordaan, DF Warner, HC Hoppe, D Laming, ...
Molecules 24 (9), 1740, 2019
182019
Anti-trypanosomal and antimalarial properties of tetralone derivatives and structurally related benzocycloalkanones
RM Beteck, LJ Legoabe, M Isaacs, SD Khanye, D Laming, HC Hoppe
Medicina 55 (5), 206, 2019
142019
Easily accessed nitroquinolones exhibiting potent and selective anti-tubercular activity
PS Dube, LJ Legoabe, A Jordaan, OJ Jesumoroti, T Tshiwawa, ...
European journal of medicinal chemistry 213, 113207, 2021
122021
An update on development of small-molecule Plasmodial kinase inhibitors
C Moolman, R Sluis, RM Beteck, LJ Legoabe
Molecules 25 (21), 5182, 2020
122020
Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors
MA Qhobosheane, LJ Legoabe, B Josselin, S Bach, S Ruchaud, ...
Bioorganic & Medicinal Chemistry 28 (11), 115468, 2020
122020
Synthesis and biological evaluation of selected 7-azaindole derivatives as CDK9/Cyclin T and Haspin inhibitors
L Pieterse, LJ Legoabe, RM Beteck, B Josselin, S Bach, S Ruchaud
102020
Synthesis, in vitro cytotoxicity and trypanocidal evaluation of novel 1,3,6-substituted non-fluoroquinolones
R.M. Beteck, M. Isaacs, H.C. Hoppe and S.D. Khanye
South Africa Journal of Chemistry 71, 188-195, 2018
9*2018
Synthesis, antiplasmodial and antitrypanosomal evaluation of a series of novel 2-oxoquinoline-based thiosemicarbazone derivatives
OT Darrell, ST Hulushe, TE Mtshare, RM Beteck, M Isaacs, D Laming, ...
South African Journal of Chemistry 71, 174-181, 2018
92018
Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors
MA Qhobosheane, RM Beteck, B Baratte, T Robert, S Ruchaud, S Bach, ...
Chemico-Biological Interactions 343, 109478, 2021
82021
In vitro Anti-Trypanosomal Activities of Indanone-Based Chalcones
Richard M. Beteck , Lesetje J. Legoabe , Michelle Isaacs
Drug Research 68 (12), 1-6, 2018
8*2018
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Articles 1–20